INTERNATIONAL HERBICIDE-RESISTANT WEED DATABASE


MUTATIONS IN HERBICIDE-RESISTANT WEEDS TO INHIBITION OF ACETOLACTATE SYNTHASE

Amino acid substitutions that confer herbicide resistance to Inhibition of Acetolactate Synthase and that were identified in herbicide-resistant weed populations. Intentionally selected (i.e., laboratory selections) are not included in this table.

Cite: Tranel, P.J., Wright, T.R, and Heap, I.M. Mutations in herbicide-resistant weeds to Inhibition of Acetolactate Synthase . Online http://www.weedscience.com. 9/29/2022.
Amino AcidSubs(1)SpeciesIMI (2)SCT (2)PTB (2)SU (2)TP (2)Year(3)Details
Ala 122 ThrXanthium strumariumRNDSSND1995Details
 ThrSolanum ptycanthumRNDNDSND2000Details
 ThrAmaranthus retroflexusRNDNDNDND2005Details
 ThrAmaranthus powelliiRNDNDSND2005Details
 ThrAmaranthus hybridus (syn: quitensis)RNDSSS2006Details
 ValApera spica-ventiNDSNDRND2011Details
 TyrRaphanus raphanistrumRNDNDRR2012Details
 ValEchinochloa crus-galli var. crus-galliRNDSNDS2013Details
 ThrEchinochloa crus-galli var. crus-galliRNDSNDR2013Details
 SerAmaranthus palmeriNDNDNDNDND2017Details
 AsnEchinochloa crus-galli var. crus-galliRNDRRR2017Details
 ThrAmaranthus palmeriNDNDNDNDND2019Details
Pro 197 ThrKochia scopariaSNDNDRR1990Details
 HisLactuca serriolarNDSRr1992Details
 ArgKochia scopariaNDNDNDRND1995Details
 LeuKochia scopariaNDNDNDRND1995Details
 GlnKochia scopariaNDNDNDRND1995Details
 SerKochia scopariaNDNDNDRND1995Details
 AlaKochia scopariaNDNDNDRND1995Details
 AlaBrassica tournefortiiSNDNDRR1999Details
 IleSisymbrium orientalerNDNDRR1999Details
 LeuAmaranthus retroflexusRNDRRR2001Details
 AlaRaphanus raphanistrumSNDNDRR2002Details
 ThrRaphanus raphanistrumSNDNDRR2002Details
 AlaLindernia dubia (=Lindernia dubia var. major)NDNDNDRND2002Details
 SerLindernia dubia (=Lindernia dubia var. major)NDNDNDRND2002Details
 GlnLindernia micranthaNDNDNDRND2002Details
 SerLindernia micranthaNDNDNDRND2002Details
 GlnLindernia procumbensNDNDNDRND2002Details
 SerLindernia procumbensNDNDNDRND2002Details
 SerAmaranthus blitoidesSNDrRr2003Details
 HisRaphanus raphanistrumSNDNDRR2003Details
 SerRaphanus raphanistrumSNDNDRR2003Details
 HisPapaver rhoeasrNDNDRS2004Details
 ThrPapaver rhoeasrNDrRr2004Details
 SerPapaver rhoeasrNDrRr2004Details
 SerBromus tectorumSRNDRND2004Details
 ThrChrysanthemum coronariumrRRRr2004Details
 SerChrysanthemum coronariumNDNDNDNDND2004Details
 SerMonochoria vaginalisNDNDNDRND2004Details
 LeuHelianthus annuusNDNDNDRND2004Details
 SerSinapis arvensisSNDNDRND2005Details
 ThrLactuca serriolarNDNDRr2006Details
 HisSchoenoplectus juncoidesSNDSRND2007Details
 SerSchoenoplectus juncoidesSNDSRND2007Details
 LeuSchoenoplectus juncoidesSNDSRND2007Details
 SerHordeum murinum ssp. leporinumSNDNDRND2007Details
 LeuThlaspi arvenserNDNDRS2007Details
 SerLolium rigidumSNDNDRND2007Details
 ThrAlopecurus myosuroidesNDNDNDRND2008Details
 ArgLolium rigidumSNDNDRND2008Details
 AlaLolium rigidumSNDNDRND2008Details
 LeuLolium rigidumSNDNDRND2008Details
 GlnLolium rigidumSNDNDRND2008Details
 LeuDescurainia sophiaNDNDNDRND2008Details
 ThrDescurainia sophiaNDNDNDRND2008Details
 ArgPapaver rhoeasrNDrRr2009Details
 LeuPapaver rhoeasRNDNDRS2009Details
 AlaPapaver rhoeasrNDrRr2009Details
 GlnStellaria mediaNDNDNDRS2010Details
 HisSchoenoplectus mucronatus (=Scirpus mucronatus)SNDSRR2010Details
 GlnSalsola tragusNDNDNDRND2010Details
 ThrApera spica-ventiNDrNDRr2011Details
 AsnApera spica-ventiNDrNDRr2011Details
 SerCapsella bursa-pastorisNDNDNDRND2011Details
 AlaDescurainia sophiaNDNDNDRND2011Details
 SerDescurainia sophiaNDNDNDRND2011Details
 LeuAnthemis cotularNDNDRr2011Details
 GlnAnthemis cotularNDNDRR2011Details
 ThrAnthemis cotularNDNDRr2011Details
 SerAnthemis cotularNDNDRR2011Details
 AlaConyza canadensisSNDRRR2011Details
 SerConyza canadensisSNDRRR2011Details
 SerApera spica-ventiNDrNDRND2011Details
 LeuSonchus asperRNDNDRND2012Details
 ThrCapsella bursa-pastorisNDNDNDRND2012Details
 HisCapsella bursa-pastorisNDNDNDRND2012Details
 LeuCapsella bursa-pastorisNDNDNDRND2012Details
 ThrHordeum murinum ssp. leporinumrNDNDRND2012Details
 SerMyosoton aquaticumSRRRr2013Details
 AlaApera spica-ventiNDNDNDRND2013Details
 ArgSchoenoplectus juncoidesSNDNDRND2013Details
 AlaSchoenoplectus juncoidesSNDNDRND2013Details
 ThrSchoenoplectus juncoidesSNDNDRND2013Details
 SerSagittaria trifoliaNDNDNDRND2014Details
 GluMyosoton aquaticumRNDRRR2015Details
 HisDescurainia sophiaNDNDNDRND2015Details
 TyrDescurainia sophiaNDNDNDRND2015Details
 ThrAlopecurus aequalisrNDNDrr2015Details
 HisCyperus difformisRNDRRR2015Details
 LeuSenecio vulgarisrrNDRS2016Details
 SerSenecio vulgarisSrNDRR2016Details
 SerCyperus compressusrNDNDRND2016Details
 AlaCyperus difformisNDNDNDRND2016Details
 SerCyperus difformisNDNDNDRND2016Details
 SerRapistrum rugosumSrrrr2016Details
 ArgLamium amplexicauleSRNDRND2016Details
 LeuGalium aparinerrrRr2016Details
 ThrGalium aparineNDNDNDRND2016Details
 SerAmaranthus palmeriNDNDNDRND2017Details
 AlaAmaranthus palmeriNDNDNDNDND2019Details
 SerGalium aparinerrrrr2019Details
 HisGalium aparinerrrrr2019Details
Ala 205 ValXanthium strumariumrNDrrr1996Details
 ValHelianthus annuusRNDNDrND2003Details
 ValAmaranthus retroflexusRNDNDSND2005Details
 ValSolanum ptycanthumRNDNDrS2007Details
 ValConyza canadensisRNDRRND2015Details
 PhePoa annuaRRRRR2016Details
Asp 376 GluAmaranthus hybridus (syn: quitensis)RRRRR2004Details
 GluKochia scopariaNDNDNDRND2008Details
 GluMonochoria vaginalisNDNDNDRND2008Details
 GluAmaranthus powelliiRRRRR2009Details
 GluConyza canadensisrNDRRR2011Details
 GluGalium spuriumNDNDNDNDR2012Details
 GluRaphanus raphanistrumrNDNDRR2012Details
 GluSchoenoplectus juncoidesrNDRRND2013Details
 GluSinapis arvensisNDNDNDrND2015Details
 GluDescurainia sophiaNDNDNDRr2015Details
 GluAmaranthus retroflexusRNDNDNDND2016Details
 GluLolium perennerRNDRR2016Details
 GluGalium aparinerrrrr2019Details
Arg 377 HisApera spica-ventiNDRNDRR2011Details
Trp 574 LeuXanthium strumariumRNDRRR1995Details
 LeuAmaranthus tuberculatus (=A. rudis)RNDNDRR1996Details
 LeuAmaranthus hybridus (syn: quitensis)RNDNDRR1997Details
 LeuKochia scopariaRNDNDRND1999Details
 LeuSisymbrium orientaleRNDNDRR1999Details
 LeuAmbrosia artemisiifoliaRNDNDRR2001Details
 LeuAmbrosia trifidaRNDNDRR2002Details
 LeuRaphanus raphanistrumNDNDNDNDND2002Details
 LeuAmaranthus blitoidesRNDRRR2003Details
 LeuCamelina microcarpaRRNDRR2004Details
 LeuAmaranthus retroflexusRNDNDRND2005Details
 LeuAmaranthus powelliiRNDNDRND2005Details
 LeuSinapis arvensisRRNDRR2005Details
 LeuSchoenoplectus juncoidesRNDRRND2007Details
 LeuLolium rigidumRNDNDRND2007Details
 LeuAlopecurus myosuroidesNDNDNDRND2008Details
 LeuBidens subalternansRNDRRR2009Details
 LeuStellaria mediaNDNDNDRR2010Details
 LeuSchoenoplectus mucronatus (=Scirpus mucronatus)RNDRRR2010Details
 LeuSalsola tragusNDNDNDRND2010Details
 LeuApera spica-ventiNDRNDRR2011Details
 LeuPapaver rhoeasNDNDNDRND2011Details
 GlyGalium aparineNDNDNDRND2011Details
 LeuGalium spuriumRNDNDNDR2012Details
 LeuPolygonum convolvulus (=Fallopia convolvulus)NDNDNDRR2012Details
 LeuEchinochloa phyllopogon (=E. oryzicola)RNDRRR2013Details
 LeuPoa annuaRNDRRND2013Details
 LeuEchinochloa crus-galli var. crus-galliRNDRRR2013Details
 MetApera spica-ventiNDNDNDRND2013Details
 LeuAlopecurus aequalisRNDNDRR2015Details
 LeuConyza canadensisRNDRRND2015Details
 LeuCyperus esculentusRNDRRR2015Details
 LeuCyperus iriaRNDRRR2015Details
 LeuSorghum halepenseNDNDNDRND2015Details
 LeuRaphanus sativusRRRRR2016Details
 LeuAmaranthus palmeriRNDRRR2016Details
 LeuChamaesyce maculataNDNDNDRND2016Details
 LeuDescurainia sophiaRRRRR2016Details
 ArgDigitaria sanguinalisRNDNDRR2017Details
 LeuGalium aparinerrrrr2019Details
 LeuLithospermum arvenseRRRRR2019Details
Ser 653 ThrAmaranthus powelliiRNDNDSND2001Details
 AsnAmaranthus tuberculatus (=A. rudis)RNDNDSS2001Details
 ThrAmaranthus tuberculatus (=A. rudis)RNDNDSS2001Details
 AsnAmaranthus hybridus (syn: quitensis)RNDRrr2006Details
 IleSetaria viridisRrRrND2009Details
 AsnSetaria viridisRrRrND2009Details
 ThrSetaria viridisRrSrND2009Details
 AsnGalium spuriumRNDNDNDS2012Details
 ThrAvena fatuaRNDNDNDND2012Details
 AsnAvena fatuaRNDNDNDND2012Details
 ThrAmaranthus retroflexusRNDNDNDND2015Details
 AsnAmaranthus palmeriNDNDNDNDND2016Details
 ThrSorghum bicolorRNDNDSND2017Details
 AsnBromus tectorumRRNDSr2017Details
Gly 654 GluOryza sativa var. sylvaticaRNDrNDND2008Details
 AspSetaria viridisRrSrND2009Details
NOTES

1. Amino acid number is standardized to the Arabidopsis thaliana sequence

2. The letters indicate the level of resistance conferred by the mutation
  • S = Susceptible biotype
  • r = Moderate resistance (< 10-fold relative to sensitive biotype)
  • R = High Resistance (> 10-fold)
  • ND = Not Determined
It should be noted that these classifications are generalizations.

3. The year that the mutation was first reported: see details for reference.
HERBICIDE FAMILY ABBREVIATIONS

IMI = Imidazolinones
SCT = Triazolinones
PTB = Pyrimidinyl benzoates
SU = Sulfonylureas
TP = Triazolopyrimidine - Type 1

This updatable table is based on the paper :
Tranel, P. J., and Wright, T. R. (2002). Resistance of weeds to ALS-inhibiting herbicides: What have we learned? WeedScience, 50: 700-712.
and is currently maintained by the authors Patrick Tranel (tranel@illinois.edu) and Terry Wright (trwright@dow.com).

If you want to add a new case, add further information to an existing case, point out an error, or just comment please click here .


PERMISSION MUST BE OBTAINED FIRST if you intend to base a significant portion of a scientific paper on data derived from this site. Citation:
Heap, I.  The International Herbicide-Resistant Weed Database.  Online.  Thursday, September 29, 2022 .  Available  www.weedscience.org Copyright © 1993- 2022 WeedScience.org All rights reserved. Fair use of this material is encouraged. Proper citation is requested.